Jury deliberations in the Karen Read retrial began Friday after weeks of testimony in the high-profile murder case that centered on the prosecution's theory of a rocky relationship that turned fatal and the defense's claim of a police cover-up. Read, 45, of Mansfield, a former adjunct professor at Bentley University, has pleaded not guilty to second-degree murder and other charges in connection with the death of John O'Keefe, her boyfriend and a Boston police officer. Prosecutors allege that Read hit O'Keefe with her SUV during a snowstorm on Jan. 29, 2022, following a night of drinking. Her first trial ended with a hung jury. Seven women and five men make up the jury, which began deliberations at 2:38 p.m. Judge Beverly Cannone reminded jurors of the prosecution's burden of proof and gave detailed instructions to the jury after each side delivered lengthy closing arguments.Defense attorney Alan Jackson opened by asserting that "there was no collision," emphasizing reasonable doubt and accusing investigators of bias and corruption. "This case was corrupted from the start. It was corrupted by biases and conflicts and personal loyalties that you heard about. And most fatally, it was corrupted by a lead investigator whose misconduct infected every single part of this case, from the top to the bottom," Jackson said.Jackson repeatedly referred to lead investigator Michael Proctor, who has since been fired from the Massachusetts State Police for writing insulting text messages about Read, and highlighted inconsistencies in the prosecution's case, including the lack of medical evidence proving O'Keefe was hit by a car."If you convict Karen Read of anything -- if you convict her of anything, science, the physics, the data -- they lose. But tragically Michael Proctor wins," Jackson said.Jackson argued that O'Keefe's injuries were more consistent with dog bites or a physical altercation, questioning why the house where O'Keefe was found was not thoroughly investigated. "We know that a person struck by a vehicle suffers massive trauma, broken bones, fractures, soft tissue damage, torn ligaments, contusions, soft tissue injuries, severe tissue injury, crushing blows. None of that was present with John. None of it. Not anywhere on his body, including his right arm. Not one bruise. Nothing. The fact is, the injuries are not from a vehicle impact," Jackson said.He also pointed to alleged favoritism toward individuals connected to law enforcement and suggested that the prosecution's timeline and evidence were flawed.Prosecutor Hank Brennan countered by focusing on Read's actions and the physical evidence. He argued that Read, intoxicated and angry, struck O'Keefe with her vehicle and left him to die. "She made a decision in her Lexus with the shattered taillight debris field all over the front yard, and John O'Keefe lying helpless like a child on that front yard. She made a choice. She didn't call 911. She didn't run to his aid. She didn't knock on a door. She made a decision about herself in her Lexus. She drove away," Brennan said.Brennan presented data from Read's SUV and O'Keefe's phone, claiming it supported the prosecution's timeline. He dismissed the defense's claims as distractions and emphasized the testimony of first responders who recalled Read admitting, "I hit him." Brennan also criticized the defense's expert witnesses, questioning their methodologies and motives. "When Karen Read, in the midst of that tension and fight after she drove away and was gone, disengaged. When she came back for the last word, in the darkness, the beginning of the snow, under the influence of alcohol, and decided to stop her Lexus. Decided to put it in reverse, decided to accelerate 75% in the exact same direction of where she left him, and then hit him, and he died. I suggest to you that is second-degree murder," Brennan said.He concluded by urging the jury to focus on the facts and hold Read accountable for her actions."Look at the facts. Look at the data. And it all leads to one person. There's no grand conspiracy. It leads to one person, the defendant. And it's not just the data and facts. It's the defendant herself," Brennan said.Video Below: Read’s father speaks outside court before closing argumentsEarlier, Read blew a kiss to supporters outside the courthouse as she arrived with her attorneys. Her father, William Read, spoke outside and said he was "feeling great.""I wish I wasn’t here, but this is what corruption is all about. Just look at the injuries. They don’t correspond to being struck by any vehicle. I want justice for John O’Keefe, but that may come at a later day. It is all about the science," he said. What to know about the case:Karen Read, 45, of Mansfield, pleaded not guilty to second-degree murder and other charges. The prosecution says she hit her boyfriend, Boston police officer John O'Keefe, with her vehicle outside of a home in Canton during a snowstorm on Jan. 29, 2022, following a night of drinking.The defense centered on allegations of a cover-up involving members of several law enforcement agencies. They say O'Keefe was beaten inside the home, bitten by a dog and then left outside.Testimony in Read's first trial began on April 29, 2024, following opening statements. It ended on July 1 when jurors reported being hopelessly deadlocked, and a mistrial was declared.Read's team vowed to keep fighting, and her defense has waged a considerable battle across multiple courts, attempting to get charges dropped or have the case thrown out entirely. Meanwhile, a federal investigation into the case concluded without any charges being filed against police.Ultimately, jury selection for Read's retrial began on April 1 and continued through April 15. Eighteen jurors were selected, and 12 of them will deliberate on the verdicts. Seven of the deliberating jurors are women, and five are men. The six alternates were separated from the group. Video: Prosecution's opening statementVideo: Defense's opening statementVideo: Prosecution's closing argumentVideo: Defense's closing statement